Biologics - Upstream Cell Line Development
Eurofins Lancaster Laboratories Professional Scientific Services, LLC

Biologics - Upstream Cell Line Development

Employee Responsibilities include, but are not limited to:

• Support the cell line development (CLD) team through participation in transfection, stable selection, cloning, expansion and characterization of mammalian cell lines for clinical and commercial production
• Perform laboratory experiments using a variety of CLD and cell culture technologies including single cell cloning/clone picking, cell imaging, liquid handling automation and Octet/ELISA-based recombinant protein quantification
• Support molecular characterization of the lead clonal cell lines for CLD programs including but not limited to mRNA analysis and gene copy number determination
• Works with departmental and/or cross functional peers to execute on assignments, under limited supervision.
• Prepares experimental protocols.
• Contributes significantly to project work which may include multiple projects within functional area.
• Interprets data independently, and contributes to technical reports
• Identifies technical issues, and implements solutions under supervision
• Contributes to the design of new applications/experiments/unit operations in consultation with supervisor.
• Coordinates within department as well as cross functionally with peers on projects.

The Ideal Candidate would possess:

• Experience in CLD technologies including culture of mammalian cells, single-cell cloning (sorting/clone picking), clonality assessment, and clone screening highly desirable
• Experience in molecular biology methods including subcloning, northern blot, RT-qPCR/ddPCR and Octet/ELISA-based recombinant protein quantification is desirable
• Ability to troubleshoot and resolve critical and routine issues using appropriate information
• Ability to work within department groups/team
• Ability to manage work load efficiently and in timely manner especially when projects are at a critical stage
• Proficiency in use of applicable lab equipment and operations; experience in maintaining written records of work in the form of laboratory notebooks (paper or electronic)
• Ability to report data, present findings to management

Minimum Qualifications:

• Bachelor's degree in biochemistry, biology, biotechnology, or related pharmaceutical science; 4+ years of biotechnology/biopharmaceutical industry experience in cell line development OR
• Master's degree in biochemistry, biology, biotechnology, or related pharmaceutical science; 1+ year of biotechnology/biopharmaceutical industry experience in cell line development
• Sound knowledge of cell culture principles, experience in aseptic techniques required
• Computer experience in common Microsoft applications (Word, Excel, PowerPoint) is required

What we offer:

• Excellent full time benefits including comprehensive medical coverage, dental, and vision options
• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays

Position is full-time, Monday-Friday, 8 a.m.-5 p.m., with overtime as needed. Candidates currently living within a commutable distance of Cambridge, Massachusetts are encouraged to apply.

Eurofins Lancaster Laboratories Professional Scientific Services ® (PSS) is a global, award-winning insourcing solution that places our people at our clients' site dedicated to running and managing laboratory services while eliminating headcount, co-employment and project-management worries.

We infuse our 55-year track record of scientific and laboratory operations expertise, as well as HR and great place to work best practices, to recruit, hire, train and manage highly qualified scientists to perform laboratory services using our client's quality systems and equipment.

Eurofins is a M/F, Disabled, and Veteran Equal Employment Opportunity and Affirmative Action employer.

---