Senior Scientist, Translational Proteomics
AstraZeneca

Senior Scientist, Translational Proteomics

Gaithersburg, MD

Join our dedicated Oncology team at AstraZeneca, where we are driven by our ambition to eliminate cancer as a cause of death. We are seeking an innovative scientist to fill a unique hybrid role that combines laboratory expertise in mass spectrometry proteomics with advanced skills in data science. This position offers an exciting opportunity to contribute to the discovery and development of novel therapeutics through the application of cutting-edge clinical proteomics.

Accountabilities:

As a Senior Scientist, you will lead design, implementation, and management of proteomics databases to organize multiple datasets derived from patient samples and clinical trials. You will serve as the primary liaison between data science teams across AZ to facilitate on-going bioinformatics collaborations with Translational Proteomics. You will also be responsible for developing, optimizing, and implementing harmonized data analysis methods and visualization of different types of data within the Translational Proteomics group for biological and clinical insight.

Essential Skills/Experience:

• Ph.D. in bioanalytical chemistry or related field with 0-3 years post-doctoral experience in quantitative mass spectrometry-based proteomics and/or computational proteomics.
• Proven expertise in mass spectrometry data analysis, proteomics data interpretation, database design and implementation for translational and clinical research.
• Proficiency in programming languages such as Python and R, and experience with statistical analysis and data visualization.
• Strong experience in quantitative proteomics software including Skyline, Spectronaut, MaxQuant, DIA-NN.
• Excellent communication skills and the ability to collaborate effectively with interdisciplinary teams.

Desirable Skills/Experience:

• Experience working in a pharmaceutical or biotechnology industry with a focus on translational and clinical research involving mass spectrometry proteomics.
• Track record of publications or contributions to the clinical research database architecture.
• Experience with automation in sample preparation and LC-MS.
• Experience working in regulated environments (GCP/GLP).

At AstraZeneca, we are a science-based, leading and decisive Oncology enterprise united in our vision to eliminate cancer as a cause of death. We push the boundaries of science to change the practice of medicine and transform the lives of patients living with cancer. With one of the broadest and deepest Oncology pipelines in the industry, there are many opportunities to work with new and novel drugs and help discover what's next. We foster a mindset of courage, where everyone is empowered to step up, innovate and work at pace. Our commitment to patients and pioneering spirit are truly embedded and it's what makes our pipeline unique.

About Our Gaithersburg Oncology Hub

Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We are dedicated to creating a culture of inclusion and collaboration.

The Gaithersburg site offers a variety of amenities to help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center, game rooms, community garden and more. This is where you'll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams.

So, what's next?

Are you ready to push the boundaries of science and change the practice of medicine? Join us at AstraZeneca and be part of our mission to eliminate cancer as a cause of death. Apply today!

If you're curious to know more, please contact Bobbi Poole, our Talent Acquisition Partner.

Closing Date: September 23, 2024

Competitive remuneration and benefits apply

We offer a competitive Total Reward program including a market driven base salary, bonus and long term incentive. We have a generous paid time off program and a comprehensive benefits package.

Where can I find out more-

Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/

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AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We follow all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

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